Ability of certain additives to influence the absorption of salicylic acid from solutions in an in vivo study: Preliminary report
The influence of polysorbates, sucrose, polyethylene glycols (PEG), propylene glycol, and dimethylsulfoxide (DMSO) on the absorption of salicylic acid has been studied. An immersion technique utilizing the frog was used. Results were analyzed by the Student t test. Certain concentrations of additive...
Gespeichert in:
| Veröffentlicht in: | Journal of pharmaceutical sciences 1967-12, Vol.56 (12), p.1661-1663 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1663 |
|---|---|
| container_issue | 12 |
| container_start_page | 1661 |
| container_title | Journal of pharmaceutical sciences |
| container_volume | 56 |
| creator | Whitworth, Clyde W. Yantis, Loudon D. |
| description | The influence of polysorbates, sucrose, polyethylene glycols (PEG), propylene glycol, and dimethylsulfoxide (DMSO) on the absorption of salicylic acid has been studied. An immersion technique utilizing the frog was used. Results were analyzed by the Student t test. Certain concentrations of additives were seen to enhance absorption. |
| doi_str_mv | 10.1002/jps.2600561227 |
| format | Article |
| fullrecord | <record><control><sourceid>wiley_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1002_jps_2600561227</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0022354915360639</els_id><sourcerecordid>JPS2600561227</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3427-512d8633ba32038f10aed939cd3917c5c0e16158b8873d44346980ccb93dab653</originalsourceid><addsrcrecordid>eNqFkctu1DAUhi0EKkNhyw7JL5Dh2I6dhF2poFyqdqSCWFqO7YhTMnFkeway5M2bKFURC8TC9uK_6JzPhLxksGUA_PXtmLZcAUjFOK8ekQ2THAoFrHpMNrOBF0KWzVPyLKVbAFAg5Qk5kbKuK15uyO-zFnvMEw0dtT5mgwM1zmHGo080B4pD1x_8YD3N3z01bQpxzBiGJZBMj3aaDzUWHe1i2NMU-sOiJ7o0Dct9xGOgKR_c9Ibuou9xj4OJE41-DDE_J0860yf_4v49JV_fv_ty_qG4vL74eH52WVhR8qqQjLtaCdEawUHUHQPjXSMa60TDKisteKaYrNt5MeHKUpSqqcHathHOtEqKU7Jde20MKUXf6THifp5DM9ALSj2j1H9QzoFXa2A8tHvvHuz37Ga9WfWf2PvpP2360-7mr-5izWLK_tdD1sQfWlWikvrb1YVuGHzeldVbvQxfr34_EzqijzpZXH7FYfQ2axfwX2vcAZFzoy8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Ability of certain additives to influence the absorption of salicylic acid from solutions in an in vivo study: Preliminary report</title><source>MEDLINE</source><source>Wiley Online Library All Journals</source><source>Alma/SFX Local Collection</source><creator>Whitworth, Clyde W. ; Yantis, Loudon D.</creator><creatorcontrib>Whitworth, Clyde W. ; Yantis, Loudon D.</creatorcontrib><description>The influence of polysorbates, sucrose, polyethylene glycols (PEG), propylene glycol, and dimethylsulfoxide (DMSO) on the absorption of salicylic acid has been studied. An immersion technique utilizing the frog was used. Results were analyzed by the Student t test. Certain concentrations of additives were seen to enhance absorption.</description><identifier>ISSN: 0022-3549</identifier><identifier>EISSN: 1520-6017</identifier><identifier>DOI: 10.1002/jps.2600561227</identifier><identifier>PMID: 5588724</identifier><language>eng</language><publisher>Washington: Elsevier Inc</publisher><subject>Animals ; Anura ; Biological Transport ; Dimethyl Sulfoxide - pharmacology ; Drug Synergism ; Fatty Acids - pharmacology ; Glycols - pharmacology ; Hydrogen-Ion Concentration ; Pharmaceutic Aids ; Propylene Glycols - pharmacology ; Salicylates - metabolism ; Skin Absorption - drug effects ; Solubility ; Solutions ; Spectrophotometry ; Statistics as Topic ; Sucrose - pharmacology ; Time Factors</subject><ispartof>Journal of pharmaceutical sciences, 1967-12, Vol.56 (12), p.1661-1663</ispartof><rights>1967 Wiley-Liss, Inc., A Wiley Company</rights><rights>Copyright © 1967 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3427-512d8633ba32038f10aed939cd3917c5c0e16158b8873d44346980ccb93dab653</citedby><cites>FETCH-LOGICAL-c3427-512d8633ba32038f10aed939cd3917c5c0e16158b8873d44346980ccb93dab653</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjps.2600561227$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjps.2600561227$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5588724$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Whitworth, Clyde W.</creatorcontrib><creatorcontrib>Yantis, Loudon D.</creatorcontrib><title>Ability of certain additives to influence the absorption of salicylic acid from solutions in an in vivo study: Preliminary report</title><title>Journal of pharmaceutical sciences</title><addtitle>J. Pharm. Sci</addtitle><description>The influence of polysorbates, sucrose, polyethylene glycols (PEG), propylene glycol, and dimethylsulfoxide (DMSO) on the absorption of salicylic acid has been studied. An immersion technique utilizing the frog was used. Results were analyzed by the Student t test. Certain concentrations of additives were seen to enhance absorption.</description><subject>Animals</subject><subject>Anura</subject><subject>Biological Transport</subject><subject>Dimethyl Sulfoxide - pharmacology</subject><subject>Drug Synergism</subject><subject>Fatty Acids - pharmacology</subject><subject>Glycols - pharmacology</subject><subject>Hydrogen-Ion Concentration</subject><subject>Pharmaceutic Aids</subject><subject>Propylene Glycols - pharmacology</subject><subject>Salicylates - metabolism</subject><subject>Skin Absorption - drug effects</subject><subject>Solubility</subject><subject>Solutions</subject><subject>Spectrophotometry</subject><subject>Statistics as Topic</subject><subject>Sucrose - pharmacology</subject><subject>Time Factors</subject><issn>0022-3549</issn><issn>1520-6017</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1967</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkctu1DAUhi0EKkNhyw7JL5Dh2I6dhF2poFyqdqSCWFqO7YhTMnFkeway5M2bKFURC8TC9uK_6JzPhLxksGUA_PXtmLZcAUjFOK8ekQ2THAoFrHpMNrOBF0KWzVPyLKVbAFAg5Qk5kbKuK15uyO-zFnvMEw0dtT5mgwM1zmHGo080B4pD1x_8YD3N3z01bQpxzBiGJZBMj3aaDzUWHe1i2NMU-sOiJ7o0Dct9xGOgKR_c9Ibuou9xj4OJE41-DDE_J0860yf_4v49JV_fv_ty_qG4vL74eH52WVhR8qqQjLtaCdEawUHUHQPjXSMa60TDKisteKaYrNt5MeHKUpSqqcHathHOtEqKU7Jde20MKUXf6THifp5DM9ALSj2j1H9QzoFXa2A8tHvvHuz37Ga9WfWf2PvpP2360-7mr-5izWLK_tdD1sQfWlWikvrb1YVuGHzeldVbvQxfr34_EzqijzpZXH7FYfQ2axfwX2vcAZFzoy8</recordid><startdate>196712</startdate><enddate>196712</enddate><creator>Whitworth, Clyde W.</creator><creator>Yantis, Loudon D.</creator><general>Elsevier Inc</general><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>196712</creationdate><title>Ability of certain additives to influence the absorption of salicylic acid from solutions in an in vivo study: Preliminary report</title><author>Whitworth, Clyde W. ; Yantis, Loudon D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3427-512d8633ba32038f10aed939cd3917c5c0e16158b8873d44346980ccb93dab653</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1967</creationdate><topic>Animals</topic><topic>Anura</topic><topic>Biological Transport</topic><topic>Dimethyl Sulfoxide - pharmacology</topic><topic>Drug Synergism</topic><topic>Fatty Acids - pharmacology</topic><topic>Glycols - pharmacology</topic><topic>Hydrogen-Ion Concentration</topic><topic>Pharmaceutic Aids</topic><topic>Propylene Glycols - pharmacology</topic><topic>Salicylates - metabolism</topic><topic>Skin Absorption - drug effects</topic><topic>Solubility</topic><topic>Solutions</topic><topic>Spectrophotometry</topic><topic>Statistics as Topic</topic><topic>Sucrose - pharmacology</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Whitworth, Clyde W.</creatorcontrib><creatorcontrib>Yantis, Loudon D.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Journal of pharmaceutical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Whitworth, Clyde W.</au><au>Yantis, Loudon D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ability of certain additives to influence the absorption of salicylic acid from solutions in an in vivo study: Preliminary report</atitle><jtitle>Journal of pharmaceutical sciences</jtitle><addtitle>J. Pharm. Sci</addtitle><date>1967-12</date><risdate>1967</risdate><volume>56</volume><issue>12</issue><spage>1661</spage><epage>1663</epage><pages>1661-1663</pages><issn>0022-3549</issn><eissn>1520-6017</eissn><abstract>The influence of polysorbates, sucrose, polyethylene glycols (PEG), propylene glycol, and dimethylsulfoxide (DMSO) on the absorption of salicylic acid has been studied. An immersion technique utilizing the frog was used. Results were analyzed by the Student t test. Certain concentrations of additives were seen to enhance absorption.</abstract><cop>Washington</cop><pub>Elsevier Inc</pub><pmid>5588724</pmid><doi>10.1002/jps.2600561227</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3549 |
| ispartof | Journal of pharmaceutical sciences, 1967-12, Vol.56 (12), p.1661-1663 |
| issn | 0022-3549 1520-6017 |
| language | eng |
| recordid | cdi_crossref_primary_10_1002_jps_2600561227 |
| source | MEDLINE; Wiley Online Library All Journals; Alma/SFX Local Collection |
| subjects | Animals Anura Biological Transport Dimethyl Sulfoxide - pharmacology Drug Synergism Fatty Acids - pharmacology Glycols - pharmacology Hydrogen-Ion Concentration Pharmaceutic Aids Propylene Glycols - pharmacology Salicylates - metabolism Skin Absorption - drug effects Solubility Solutions Spectrophotometry Statistics as Topic Sucrose - pharmacology Time Factors |
| title | Ability of certain additives to influence the absorption of salicylic acid from solutions in an in vivo study: Preliminary report |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T09%3A02%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-wiley_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Ability%20of%20certain%20additives%20to%20influence%20the%20absorption%20of%20salicylic%20acid%20from%20solutions%20in%20an%20in%20vivo%20study:%20Preliminary%20report&rft.jtitle=Journal%20of%20pharmaceutical%20sciences&rft.au=Whitworth,%20Clyde%20W.&rft.date=1967-12&rft.volume=56&rft.issue=12&rft.spage=1661&rft.epage=1663&rft.pages=1661-1663&rft.issn=0022-3549&rft.eissn=1520-6017&rft_id=info:doi/10.1002/jps.2600561227&rft_dat=%3Cwiley_cross%3EJPS2600561227%3C/wiley_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/5588724&rft_els_id=S0022354915360639&rfr_iscdi=true |