Decreasing seroprevalence of anti‐hepatitis D virus antibodies in the antiviral era with inverse association with hepatitis B virus DNA, Taiwan, 2006 to 2019

Decreasing seroprevalence of anti‐hepatitis D virus antibodies in the antiviral era with inverse association with hepatitis B virus DNA, Taiwan, 2006 to 2019

We examined the seroprevalence change of anti‐hepatitis D virus (HDV) antibodies in Taiwan from 2006 to 2019. A total of 1147 patients who had chronic hepatitis B virus (HBV) infection were assessed. Of them, 51 (4.4%) were positive for anti‐HDV antibodies. Comparison between anti‐HDV‐positive and n...

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Veröffentlicht in:Journal of medical virology 2020-01, Vol.92 (1), p.124-127
Hauptverfasser: Lee, Kuan‐Chieh, Lin, Chih‐Lang, Hsu, Chao‐Wei, Chang, Ming‐Ling, Chen, Yi‐Cheng, Lin, Wey‐Ran, Lai, Ming‐Wei, Lin, Kwang‐Huei, Chao, Mei, Chien, Rong‐Nan, Yeh, Chau‐Ting
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Antibodies
Chronic infection
Coinfection - epidemiology
Coinfection - immunology
Coinfection - virology
Deoxyribonucleic acid
DNA
DNA, Viral - blood
Female
Hepatitis
Hepatitis Antibodies - blood
Hepatitis B
hepatitis B virus
Hepatitis B virus - genetics
Hepatitis B, Chronic - epidemiology
Hepatitis B, Chronic - immunology
Hepatitis D - epidemiology
Hepatitis D - immunology
hepatitis delta
Hepatitis delta virus
Humans
Immunoglobulins
Interferon
Male
Middle Aged
Retrospective Studies
Seroepidemiologic Studies
Serology
Taiwan - epidemiology
viral load
Virology
Viruses
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Zusammenfassung:We examined the seroprevalence change of anti‐hepatitis D virus (HDV) antibodies in Taiwan from 2006 to 2019. A total of 1147 patients who had chronic hepatitis B virus (HBV) infection were assessed. Of them, 51 (4.4%) were positive for anti‐HDV antibodies. Comparison between anti‐HDV‐positive and negative groups was performed to examine clinical and virological factors related to anti‐HDV positivity. It was found that the median HBV‐DNA concentration was 1.6 × 105 IU/mL (range,
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.25582