The Role of Improved Motion-Sensitized Driven Equilibrium Blood Suppression and Fat Saturation on T 2 Relaxation Time, Using GraSE Sequence in Cardiac Magnetic Resonance Imaging

T mapping is a valuable technique in cardiac MR imaging that offers insights into the microstructural characteristics of myocardial tissue. However, it was shown that myocardial T relaxation times (T ) measured vary significantly depending on sequence, sequence parameters, and field strength. To assess T variability and image quality in cardiac T maps using four variants of the gradient-spin echo (GraSE) sequence, having different methods of blood signal suppression (double inversion recovery (DIR) and improved motion-sensitized driven equilibrium (iMSDE) and with and without the addition of fat saturation (FS). Prospective. 48 healthy volunteers (46.7 +/- 21.5 years, 24 male) with no cardiac history. GraSE sequence with DIR (GraSE ), with iMSDE (GraSE ) and FS (GraSE -FS) and with both iMSDE and FS (GraSE -FS) at 1.5T. Global T from three short axis myocardial slices. and image quality assessments using a 5-point Lickert scale (1, (non-diagnostic) to 5, (excellent)) were conducted to evaluate the impact of DB and FS techniques on myocardial T measurements and image quality. Paired t-tests or non-parametric equivalents for comparisons between sequences. The Bland-Altmann plots and Pearson rank correlation analyses, as appropriate. A P value 4 out of 5) were obtained for all sequence variants with no significant differences between them (P = 0.11). All GraSE sequence variants exhibited approximately the same results and variations in the DB technique and addition of FS did not have significant impact on myocardial T values. 2 TECHNICAL EFFICACY: Stage 1.