Synthesis of [3′‐ 14 C] coenzyme Q 10
Radio‐labelled coenzyme Q 10 , labelled at the 3′‐position with 14 C, was synthesized starting from natural solanesol and ethyl [3‐ 14 C] acetoacetate. The radiochemical yield was 8.0% from ethyl [3‐ 14 C] acetoacetate. The specific radioactivity of the product was 44.8 μCi, 1.66 MBq/mg. The specifi...
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| Veröffentlicht in: | Journal of labelled compounds & radiopharmaceuticals 2002-09, Vol.45 (10), p.823-829 |
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| container_title | Journal of labelled compounds & radiopharmaceuticals |
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| creator | Hamamura, Kimio Yamatsu, Isao Minami, Norio Yamagishi, Yoji Inai, Yuichi Kijima, Shizumasa Nakamura, Tetsuya |
| description | Radio‐labelled coenzyme Q
10
, labelled at the 3′‐position with
14
C, was synthesized starting from natural solanesol and ethyl [3‐
14
C] acetoacetate. The radiochemical yield was 8.0% from ethyl [3‐
14
C] acetoacetate. The specific radioactivity of the product was 44.8 μCi, 1.66 MBq/mg. The specific radioactivity and radiochemical purity are sufficiently high to enable us to use this labelled form of coenzyme Q
10
in metabolic studies. Copyright © 2002 John Wiley & Sons, Ltd. |
| doi_str_mv | 10.1002/jlcr.588 |
| format | Article |
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10
, labelled at the 3′‐position with
14
C, was synthesized starting from natural solanesol and ethyl [3‐
14
C] acetoacetate. The radiochemical yield was 8.0% from ethyl [3‐
14
C] acetoacetate. The specific radioactivity of the product was 44.8 μCi, 1.66 MBq/mg. The specific radioactivity and radiochemical purity are sufficiently high to enable us to use this labelled form of coenzyme Q
10
in metabolic studies. Copyright © 2002 John Wiley & Sons, Ltd.</description><identifier>ISSN: 0362-4803</identifier><identifier>EISSN: 1099-1344</identifier><identifier>DOI: 10.1002/jlcr.588</identifier><language>eng</language><ispartof>Journal of labelled compounds & radiopharmaceuticals, 2002-09, Vol.45 (10), p.823-829</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c728-ed68c1e338689d4df34f1c0b6626f906a44994bb20c1d009fdf0b83877e821ac3</citedby><cites>FETCH-LOGICAL-c728-ed68c1e338689d4df34f1c0b6626f906a44994bb20c1d009fdf0b83877e821ac3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Hamamura, Kimio</creatorcontrib><creatorcontrib>Yamatsu, Isao</creatorcontrib><creatorcontrib>Minami, Norio</creatorcontrib><creatorcontrib>Yamagishi, Yoji</creatorcontrib><creatorcontrib>Inai, Yuichi</creatorcontrib><creatorcontrib>Kijima, Shizumasa</creatorcontrib><creatorcontrib>Nakamura, Tetsuya</creatorcontrib><title>Synthesis of [3′‐ 14 C] coenzyme Q 10</title><title>Journal of labelled compounds & radiopharmaceuticals</title><description>Radio‐labelled coenzyme Q
10
, labelled at the 3′‐position with
14
C, was synthesized starting from natural solanesol and ethyl [3‐
14
C] acetoacetate. The radiochemical yield was 8.0% from ethyl [3‐
14
C] acetoacetate. The specific radioactivity of the product was 44.8 μCi, 1.66 MBq/mg. The specific radioactivity and radiochemical purity are sufficiently high to enable us to use this labelled form of coenzyme Q
10
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10
, labelled at the 3′‐position with
14
C, was synthesized starting from natural solanesol and ethyl [3‐
14
C] acetoacetate. The radiochemical yield was 8.0% from ethyl [3‐
14
C] acetoacetate. The specific radioactivity of the product was 44.8 μCi, 1.66 MBq/mg. The specific radioactivity and radiochemical purity are sufficiently high to enable us to use this labelled form of coenzyme Q
10
in metabolic studies. Copyright © 2002 John Wiley & Sons, Ltd.</abstract><doi>10.1002/jlcr.588</doi><tpages>7</tpages></addata></record> |
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| source | Wiley Online Library All Journals |
| title | Synthesis of [3′‐ 14 C] coenzyme Q 10 |
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