Synthesis of [3H]cyfluthrin

Synthesis of [3H]cyfluthrin

For the elucidation of the distribution and biotransformation of Cyfluthrin in tse‐tse flies the tritium‐labelled compound was needed. A brominated precursor was dehalogenated with tritium gas using a special noble metal catalyst to give the desired [3H]Cyfluthrin. The labelling position was confirm...

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Veröffentlicht in:Journal of labelled compounds & radiopharmaceuticals 1993-10, Vol.33 (10), p.949-955
Hauptverfasser: Pleiß, Ulrich, Römer, Johannes, Thomas, Rudolf
Format: Artikel
Sprache:eng
Schlagworte:
[3H]Cyfluthrin
Alicyclic compounds
Alicyclic compounds, terpenoids, prostaglandins, steroids
Chemistry
dehalogenation
Exact sciences and technology
Organic chemistry
Preparations and properties
tritium labelling
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Beschreibung
Zusammenfassung:For the elucidation of the distribution and biotransformation of Cyfluthrin in tse‐tse flies the tritium‐labelled compound was needed. A brominated precursor was dehalogenated with tritium gas using a special noble metal catalyst to give the desired [3H]Cyfluthrin. The labelling position was confirmed by 3H‐NMR spectroscopy. After synthesis and purification, the [3H]Cyfluthrin obtained showed a specific activity of 23.7 Ci/ mmol (877 GBq/mmol).
ISSN:0362-4803
1099-1344
DOI:10.1002/jlcr.2580331009