Labelled compounds of potential biological interest. IV. Tritium labelling of some cyclzing compounds

Quaternary ammonium compounds formed at the site of action by spontaneous cyclization of tertiary ω‐haloalkylamine precursors may have interesting pharmacological properties. In order to study the pharmacokinetics of the cyclization principle, a series of new tertiary ω‐haloalkylamines derived from p‐chloroamphetamine has been synthesized both unlabelled and labelled with tritium at high specific activity.