Synthesis of deuterium-labelled standards of (±)-DOM and (±)-MMDA

Synthesis of deuterium-labelled standards of (±)-DOM and (±)-MMDA

This study describes the synthesis of deuterium‐labelled (±)‐4‐methyl‐2,5‐dimethoxyamphetamine (DOM) and (±)‐1‐(7‐methoxy‐1,3‐benzodioxol‐5‐yl)propan‐2‐amine (MMDA). The isotopically labelled compounds are potentially used as internal standards in gas chromatography–mass spectrometry (GC–MS) assays....

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Veröffentlicht in:Journal of labelled compounds & radiopharmaceuticals 2007-06, Vol.50 (7), p.660-665
Hauptverfasser: Shaikh, Ajam C., Wang, Yu-Yun, Chen, Chinpiao
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
deuterium labelled
DOM
Drug addictions
internal standard
Medical sciences
MMDA
Toxicology
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Zusammenfassung:This study describes the synthesis of deuterium‐labelled (±)‐4‐methyl‐2,5‐dimethoxyamphetamine (DOM) and (±)‐1‐(7‐methoxy‐1,3‐benzodioxol‐5‐yl)propan‐2‐amine (MMDA). The isotopically labelled compounds are potentially used as internal standards in gas chromatography–mass spectrometry (GC–MS) assays. Copyright © 2007 John Wiley & Sons, Ltd. This study describes the synthesis of deuterium‐labelled (±)‐4‐methyl‐2,5‐dimethoxyamphetamine (DOM) and (±)‐1‐(7‐methoxy‐1,3‐benzodioxol‐5‐yl)propan‐2‐amine (MMDA). The isotopically labelled compounds are potentially used as internal standards in gas chromatography–mass spectrometry (GC–MS) assays. Copyright © 2007 John Wiley & Sons, Ltd.
ISSN:0362-4803
1099-1344
DOI:10.1002/jlcr.1378