An expeditious one-pot synthesis of substituted phenylazetidin-2-ones in the presence of zeolite

In this study, one‐pot rapid and efficient series of phenylazetidin‐2‐ones were synthesized from N,N‐dimethylaminobenzaldehyde, different substituted aromatic amines and phenylacetyl chloride in the presence of zeolite catalyst under microwave irradiation. We also reported schiff bases (1a–j) by cla...

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Veröffentlicht in:Journal of heterocyclic chemistry 2011-09, Vol.48 (5), p.1067-1072
Hauptverfasser: Pagadala, Ramakanth, Meshram, Jyotsna S., Chopde, Himani N., Jetti, Venkateshwarlu, Udayini, V.
Format: Artikel
Sprache:eng
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Zusammenfassung:In this study, one‐pot rapid and efficient series of phenylazetidin‐2‐ones were synthesized from N,N‐dimethylaminobenzaldehyde, different substituted aromatic amines and phenylacetyl chloride in the presence of zeolite catalyst under microwave irradiation. We also reported schiff bases (1a–j) by classical and conventional microwave technique. The titled compounds are evaluated for their antimicrobial properties. The activities are due to CO, CN, linkages in 2‐azetidinones. All the compounds have shown comparable antibacterial activities. J. Heterocyclic Chem., (2011).
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.604