Convenient preparations of 2-alkyl-5-oxopyrrolidine-3-carboxylic acids
Reduction of the Michael addition products of anions of nitro compounds to dimethyl maleate led to the spontaneous formation of the respective 2‐alkyl‐5‐oxopyrrolidine‐3‐carboxylic acid methyl esters. Conventional hydrolysis of the later gave the desired compounds.
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| Veröffentlicht in: | Journal of heterocyclic chemistry 2008-07, Vol.45 (4), p.1251-1253 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Reduction of the Michael addition products of anions of nitro compounds to dimethyl maleate led to the spontaneous formation of the respective 2‐alkyl‐5‐oxopyrrolidine‐3‐carboxylic acid methyl esters. Conventional hydrolysis of the later gave the desired compounds. |
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| ISSN: | 0022-152X 1943-5193 |
| DOI: | 10.1002/jhet.5570450454 |