Synthesis of a new class of spiro heterocycles

Synthesis of a new class of spiro heterocycles

A new class of spiro heterocycles viz., spiropyrazolidinediones, isoxazolidinediones, pyrimidinetriones or thioxopyrimidinediones are developed from methyl 3‐aryl‐2‐(Z‐arylethenenylsulfonyl)acrylate by double Michael addition reaction with dimethyl malonate followed by cyclocondensation with appropr...

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Veröffentlicht in:Journal of heterocyclic chemistry 2008-03, Vol.45 (2), p.513-519
Hauptverfasser: Padmavathi, Venkatapuram, Sudheer, Kaveti, Subbaiah, Dandu Rangayapalle Chinna Venkata, Mahesh, Konda
Format: Artikel
Sprache:eng
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Zusammenfassung:A new class of spiro heterocycles viz., spiropyrazolidinediones, isoxazolidinediones, pyrimidinetriones or thioxopyrimidinediones are developed from methyl 3‐aryl‐2‐(Z‐arylethenenylsulfonyl)acrylate by double Michael addition reaction with dimethyl malonate followed by cyclocondensation with appropriate nucleophiles.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.5570450233