Synthesis of 4-amino-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-5-ol derivatives

This paper describes the synthesis of 4‐amino‐5,6,7,8‐tetrahydrothieno[2,3‐b]quinolin‐5‐ol derivatives (3a‐h) and 4‐amino‐5,6,7,8‐tetrahydrothieno[2,3‐b]quinoline (8a) in good yield by three‐step procedures starting from 2‐aminothiophene‐3‐carbonitrile and 5‐substituted cyclohexane‐1,3‐dione....

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Veröffentlicht in:Journal of heterocyclic chemistry 2007-11, Vol.44 (6), p.1439-1443
Hauptverfasser: Song, Yang-Heon, Seo, Jinmoo
Format: Artikel
Sprache:eng
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Zusammenfassung:This paper describes the synthesis of 4‐amino‐5,6,7,8‐tetrahydrothieno[2,3‐b]quinolin‐5‐ol derivatives (3a‐h) and 4‐amino‐5,6,7,8‐tetrahydrothieno[2,3‐b]quinoline (8a) in good yield by three‐step procedures starting from 2‐aminothiophene‐3‐carbonitrile and 5‐substituted cyclohexane‐1,3‐dione.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.5570440631