Pictet-spengler cyclization in room temperature ionic liquid: A convenient access to tetrahydro β-carbolines

1,2,3,4‐Tetrahydro‐β‐carbolines have been synthesized in moderate to good yields in short reaction time using the ionic liquid [bbim] BF4 as reaction medium and promoter. There was no need for the use of an additional catalyst normally employed in Pictet‐Spengler condensation.

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Veröffentlicht in:Journal of heterocyclic chemistry 2006-05, Vol.43 (3), p.767-772
Hauptverfasser: Muthukrishnan, M., More, Shivaji V., Garud, Dinesh R., Ramana, C. V., Joshi, R. R., Joshi, R. A.
Format: Artikel
Sprache:eng
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Zusammenfassung:1,2,3,4‐Tetrahydro‐β‐carbolines have been synthesized in moderate to good yields in short reaction time using the ionic liquid [bbim] BF4 as reaction medium and promoter. There was no need for the use of an additional catalyst normally employed in Pictet‐Spengler condensation.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.5570430337