A stereoselective three-component reaction: One-pot synthesis of cis-isoquinolonic acids catalyzed by silica sulfuric acid under mild and heterogeneous conditions
A mild and stereoselective three‐component one‐step synthesis of cis‐isoquinolonic acid using silica sulfuric acid as a heterogeneous catalyst from an aldehyde, amine and homophthalic anhydride in acetonitrile is described. This new method produces pure products in high yields (81‐91%).
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| Veröffentlicht in: | Journal of heterocyclic chemistry 2006-01, Vol.43 (1), p.187-190 |
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| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | A mild and stereoselective three‐component one‐step synthesis of cis‐isoquinolonic acid using silica sulfuric acid as a heterogeneous catalyst from an aldehyde, amine and homophthalic anhydride in acetonitrile is described. This new method produces pure products in high yields (81‐91%). |
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| ISSN: | 0022-152X 1943-5193 |
| DOI: | 10.1002/jhet.5570430129 |