New molecular entities via intermolecular meta photocycloaddition

The intermolecular meta photocycloaddition of 1,3‐dihydroisobenzofuran and 1,3‐dihydroisoindole‐2‐carboxylic acid methyl ester with cyclopentene and 2,5‐dihydrofuran affords two new classes of photoadducts. The photoadducts were identified by the SORT&gen algorithm as New Molecular Entities in two‐dimensional scaffold space. The structures of the adducts were established by NMR spectroscopy and the stereo‐, regio‐ and chemoselectivity of the reactions is discussed.