Alkylation of 2-pyridinones: Synthesis of novel acyclonucleosides
This paper presents the synthesis of some novel acyclonucleosides containing 2‐pyridinones and 2‐hydroxyethoxymethyl, 2,3‐dihydroxy‐propyl side chain. The tosylate of these nucleosides analogues could be modified to azido derivatives. Also, acyclonucleosides with 1‐ethoxymethyl, 1‐benzyloxymethyl, 1...
Gespeichert in:
| Veröffentlicht in: | Journal of heterocyclic chemistry 2004-05, Vol.41 (3), p.311-316 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | This paper presents the synthesis of some novel acyclonucleosides containing 2‐pyridinones and 2‐hydroxyethoxymethyl, 2,3‐dihydroxy‐propyl side chain. The tosylate of these nucleosides analogues could be modified to azido derivatives. Also, acyclonucleosides with 1‐ethoxymethyl, 1‐benzyloxymethyl, 1‐methylthiomethy 1 and 2‐hydroxyethyl side chains have been investigated. The O‐alkylated pyridine derivatives were obtained during most reactions. |
|---|---|
| ISSN: | 0022-152X 1943-5193 |
| DOI: | 10.1002/jhet.5570410302 |