Synthesis of side-chain-substituted ifosfamide analogs

Synthesis of side-chain-substituted ifosfamide analogs

Three analogs of the cytostatic drug ifosfamide incorporating 1‐methyl‐2‐chloroethyl side chains were designed and prepared as an attempt to obtain drugs of lower toxicity.

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Veröffentlicht in:Journal of heterocyclic chemistry 2001-09, Vol.38 (5), p.1131-1134
Hauptverfasser: Paci, Angelo, Guillaume, Dominique, Husson, Henri-Philippe
Format: Artikel
Sprache:eng
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Zusammenfassung:Three analogs of the cytostatic drug ifosfamide incorporating 1‐methyl‐2‐chloroethyl side chains were designed and prepared as an attempt to obtain drugs of lower toxicity.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.5570380517