New 2‐substituted 4‐hydroxy‐2 H ‐1,2‐benzothiazine‐3‐carboxamide 1,1‐dioxides: Spectral and pharmacological properties

New 2‐substituted 4‐hydroxy‐2 H ‐1,2‐benzothiazine‐3‐carboxamide 1,1‐dioxides: Spectral and pharmacological properties

A series of 4‐hydroxy‐2 H ‐1,2‐benzothiazme‐3‐carboxamide 1,1‐dioxides substituted on the sulfonamide nitrogen with ethoxycarbonylalkyl, cyanoalkyl and dialkylaminoalkyl groups was synthesized. Spectroscopic properties of the obtained products were analyzed. Findings from the pharmacological study o...

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Veröffentlicht in:Journal of heterocyclic chemistry 1999-05, Vol.36 (3), p.803-811
Hauptverfasser: Maso, Monica Dal, Perillo, Isabel A., Schapira, Celia B., Gorzalczany, Susana, Acevedo, María C., Sicardi, Susana M.
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container_end_page 811
container_issue 3
container_start_page 803
container_title Journal of heterocyclic chemistry
container_volume 36
creator Maso, Monica Dal
Perillo, Isabel A.
Schapira, Celia B.
Gorzalczany, Susana
Acevedo, María C.
Sicardi, Susana M.
description A series of 4‐hydroxy‐2 H ‐1,2‐benzothiazme‐3‐carboxamide 1,1‐dioxides substituted on the sulfonamide nitrogen with ethoxycarbonylalkyl, cyanoalkyl and dialkylaminoalkyl groups was synthesized. Spectroscopic properties of the obtained products were analyzed. Findings from the pharmacological study of some of the compounds as antiinflammatory and analgesic agents are reported.
doi_str_mv 10.1002/jhet.5570360338
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title New 2‐substituted 4‐hydroxy‐2 H ‐1,2‐benzothiazine‐3‐carboxamide 1,1‐dioxides: Spectral and pharmacological properties
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