New 2‐substituted 4‐hydroxy‐2 H ‐1,2‐benzothiazine‐3‐carboxamide 1,1‐dioxides: Spectral and pharmacological properties

New 2‐substituted 4‐hydroxy‐2 H ‐1,2‐benzothiazine‐3‐carboxamide 1,1‐dioxides: Spectral and pharmacological properties

A series of 4‐hydroxy‐2 H ‐1,2‐benzothiazme‐3‐carboxamide 1,1‐dioxides substituted on the sulfonamide nitrogen with ethoxycarbonylalkyl, cyanoalkyl and dialkylaminoalkyl groups was synthesized. Spectroscopic properties of the obtained products were analyzed. Findings from the pharmacological study o...

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Veröffentlicht in:Journal of heterocyclic chemistry 1999-05, Vol.36 (3), p.803-811
Hauptverfasser: Maso, Monica Dal, Perillo, Isabel A., Schapira, Celia B., Gorzalczany, Susana, Acevedo, María C., Sicardi, Susana M.
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Sprache:eng
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Zusammenfassung:A series of 4‐hydroxy‐2 H ‐1,2‐benzothiazme‐3‐carboxamide 1,1‐dioxides substituted on the sulfonamide nitrogen with ethoxycarbonylalkyl, cyanoalkyl and dialkylaminoalkyl groups was synthesized. Spectroscopic properties of the obtained products were analyzed. Findings from the pharmacological study of some of the compounds as antiinflammatory and analgesic agents are reported.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.5570360338