Castration-induced prostate epithelial cell apoptosis results from targeted oxidative stress attack of M1 142 -macrophages

Prostate development and function are regulated by androgens. Epithelial cell apoptosis in response to androgen deprivation is caspase-9-dependent and peaks at Day 3 after castration. However, isolated epithelial cells survive in the absence of androgens. Znf142 showed an on-off expression pattern i...

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Veröffentlicht in:Journal of cellular physiology 2019-10, Vol.234 (10), p.19048-19058
Hauptverfasser: Barbosa, Guilherme O, Silva, Juliete A F, Siqueira-Berti, Aline, Nishan, Umar, Rosa-Ribeiro, Rafaela, Oliveira, Silvia B P, Baratti, Mariana O, Ferrucci, Danilo, Santana, Julio C O, Damas-Souza, Danilo M, Bruni-Cardoso, Alexandre, Augusto, Taize M, Corrêa-da-Silva, Felipe, Moraes-Vieira, Pedro M, Stach-Machado, Dagmar R, Felisbino, Sergio L, Menezes, Gustavo B, Cesar, Carlos L, Carvalho, Hernandes F
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Sprache:eng
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