Synthesis of Imidazo[2,1-a]isoquinolines from α-Tosyloxyketones and 1-Aminoisoquinoline in Ionic Liquid Solvent

The room temperature ionic liquid n‐butylpyridinium tetrafluoroborate (BPyBF4) is used as a ‘green’ recyclable alternative to classical molecular solvents for the cyclocondensation of α‐tosyloxyketones with 1‐aminoisoquinoline to prepare imidazo[2,1‐a]isoquinolines in good yields.

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Veröffentlicht in:Journal of the Chinese Chemical Society (Taipei) 2004-12, Vol.51 (6), p.1417-1420
Hauptverfasser: Hou, Rei-Sheu, Wang, Huey-Min, Huang, Hsin-Yu, Chen, Ling-Ching
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Sprache:eng
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Zusammenfassung:The room temperature ionic liquid n‐butylpyridinium tetrafluoroborate (BPyBF4) is used as a ‘green’ recyclable alternative to classical molecular solvents for the cyclocondensation of α‐tosyloxyketones with 1‐aminoisoquinoline to prepare imidazo[2,1‐a]isoquinolines in good yields.
ISSN:0009-4536
2192-6549
DOI:10.1002/jccs.200400208