New Regioselective Synthesis and Biological Activity of Substituted 1H-[1,2,4]Triazolo[3,4-c][1,2,4]Triazoles

Two regioselective synthetic approaches for the title compounds 7 via reaction of hydrazonoyl halides 1 with 3‐methylthio‐5‐phenyl‐1,2,4‐triazole 3 and base‐catalyzed cyclization of N‐phenyl‐N‐(5‐phenyl‐s‐triazol‐3‐yl)thiohydrazides 6 are described. The mechanisms of the reactions studied and the bi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of the Chinese Chemical Society (Taipei) 2004-04, Vol.51 (2), p.351-357
Hauptverfasser: Shawali, A. S., Abdallah, M. A., Abbas, I. M., Eid, G. M.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Two regioselective synthetic approaches for the title compounds 7 via reaction of hydrazonoyl halides 1 with 3‐methylthio‐5‐phenyl‐1,2,4‐triazole 3 and base‐catalyzed cyclization of N‐phenyl‐N‐(5‐phenyl‐s‐triazol‐3‐yl)thiohydrazides 6 are described. The mechanisms of the reactions studied and the biological activity of the isolated products 6 and 7 are pointed out.
ISSN:0009-4536
2192-6549
DOI:10.1002/jccs.200400054