Apatite formation in the reaction‐setting mixture of Ca(OH) 2 KH 2 PO 4 system

Development of a new calcium phosphate cement (CPC) system as an alternative to that commonly used, basically consisting of tetracalcium phosphate and dicalcium phosphate self‐setting mixtures, could be of interest in achieving special properties of the product. Powder mixtures of Ca(OH) 2 and KH 2 PO 4 were studied to assess their potential for the precipitation of apatite‐like phase with the use of potassium phosphate salt solution as the cement liquid. X‐ray diffraction and infrared (IR) spectroscopy studies and pH and setting time measurements were performed. The set cement was revealed to consist of a low crystalline carbonate‐substituted apatite‐like phase. The setting time of the cement was about 5 min. Its dissolution in distilled water led to an increase in solution pH to about 11.5, the pH slowly decreasing to 10.2 at day 10. The results showed the cement to be of an increased carbonate substitution ability compared to the tetracalcium phosphate–dicalcium phosphate anhydrous cement. © 2004 Wiley Periodicals, Inc. J Biomed Mater Res 70A: 303–308, 2004