Frequent elevation of tissue polypeptide antigen in the sera of workers exposed to bladder carcinogens

Frequent elevation of tissue polypeptide antigen in the sera of workers exposed to bladder carcinogens

A group of 108 male workers previously exposed to bladder carcinogens and a group of 26 patients with carcinoma of the bladder differed significantly from a control group comprising 63 healthy male donors with respect to their levels of tissue polypeptide antigen (TPA). The risk group exhibited 4–6...

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Veröffentlicht in:International journal of cancer 1978-11, Vol.22 (5), p.542-545
Hauptverfasser: Kumar, Shant, Wilson, Philip, Brenchley, Paul, Taylor, Geoffrey, Björklund, Bertil, Eklund, Gunnar
Format: Artikel
Sprache:eng
Schlagworte:
2-Naphthylamine - adverse effects
Adult
Aged
Antigens - analysis
Benzidines - adverse effects
Carcinogens
Environmental Exposure
Epitopes
Female
Hemagglutination Inhibition Tests
Humans
Male
Middle Aged
Naphthalenes - adverse effects
Occupational Diseases - chemically induced
Occupational Diseases - immunology
Peptides - analysis
Prognosis
Urinary Bladder Neoplasms - chemically induced
Urinary Bladder Neoplasms - immunology
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Zusammenfassung:A group of 108 male workers previously exposed to bladder carcinogens and a group of 26 patients with carcinoma of the bladder differed significantly from a control group comprising 63 healthy male donors with respect to their levels of tissue polypeptide antigen (TPA). The risk group exhibited 4–6 times more frequent elevations of TPA than did the group of healthy donors.
ISSN:0020-7136
1097-0215
DOI:10.1002/ijc.2910220506