Transformation of mouse cells after infection with ultraviolet irradiation‐inactivated herpes simplex virus type 2

A transformed mouse cell line (H238) was obtained following the infection of 238 mouse cells with ultraviolet (UV) irradiation‐inactivated herpes simplex virus type 2 (HSV‐2). The transformed cells produced tumors with a 100% incidence within 8 weeks in 6‐week‐old syngeneic BALB/c mice at an inoculu...

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Veröffentlicht in:	International journal of cancer 1975-10, Vol.16 (4), p.526-538
Hauptverfasser:	Boyd, Ann Lewis, Orme, Thomas W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Viral Antibody Specificity Antigens, Viral Cell Line Cell Transformation, Neoplastic DNA, Neoplasm - isolation & purification DNA, Viral - isolation & purification In Vitro Techniques Mice Mice, Inbred BALB C Neoplasm Transplantation Neoplasms, Experimental - immunology Neutralization Tests Radiation Effects Simplexvirus - immunology Simplexvirus - radiation effects Transplantation, Isogeneic Ultraviolet Rays
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