Multicomponent Approach Towards the Synthesis of Substituted Pyrroles under Supramolecular Catalysis Using β-Cyclodextrin as a Catalyst in Water Under Neutral Conditions

Synthesis of substituted pyrroles in H2O by using β‐cyclodextrin as a supramolecular catalyst is described. This reaction has several advantages over existing methods and provides substituted pyrroles in good‐to‐excellent yields (79–89%). The supramolecular catalysis of the reaction was studied using 1H‐NMR spectroscopy. β‐Cyclodextrin can be recovered and reused several times without loss of activity.