Stereoselective Total Synthesis of Xestodecalactone C

Stereoselective Total Synthesis of Xestodecalactone C

A simple and highly efficient stereoselective total synthesis of xestodecalactone C (IIb), a polyketide natural product, was achieved (Scheme 2). The synthesis involved Keck's asymmetric allylation, a iodine‐induced electrophilic cyclization, and an intramolecular Friedel–Crafts acylation as ke...

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Veröffentlicht in:Helvetica chimica acta 2009-09, Vol.92 (9), p.1866-1872
Hauptverfasser: Rajesh, Karuturi, Suresh, Vangaru, Selvam, Jondoss Jon Paul, Bhujanga Rao, Chitturi, Venkateswarlu, Yenamandra
Format: Artikel
Sprache:eng
Schlagworte:
Cyclization reactions
Friedel - Crafts acylation
Keck's allylation
Xestodecalactone C
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Zusammenfassung:A simple and highly efficient stereoselective total synthesis of xestodecalactone C (IIb), a polyketide natural product, was achieved (Scheme 2). The synthesis involved Keck's asymmetric allylation, a iodine‐induced electrophilic cyclization, and an intramolecular Friedel–Crafts acylation as key steps.
ISSN:0018-019X
1522-2675
DOI:10.1002/hlca.200900068