New Acyclic 12-Hydroxygeranylgeraniol-Derived Diterpenoids from the Seeds of Carpesium triste

New Acyclic 12-Hydroxygeranylgeraniol-Derived Diterpenoids from the Seeds of Carpesium triste

Five new acyclic 12‐hydroxygeranylgeraniol‐derived diterpenoids, i.e., 1–5, were isolated from the seeds of Carpesium triste. The structures including the absolute configurations of the new compounds were elucidated by spectroscopic methods. All the compounds, except for 2, were evaluated for their...

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Veröffentlicht in:Helvetica chimica acta 2008-10, Vol.91 (10), p.1934-1939
Hauptverfasser: Gao, Xue, Zhang, Zhan-Xin, Jia, Zhong-Jian
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Carpesium triste
Cytotoxic activity
Diterpenoids
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container_end_page 1939
container_issue 10
container_start_page 1934
container_title Helvetica chimica acta
container_volume 91
creator Gao, Xue
Zhang, Zhan-Xin
Jia, Zhong-Jian
description Five new acyclic 12‐hydroxygeranylgeraniol‐derived diterpenoids, i.e., 1–5, were isolated from the seeds of Carpesium triste. The structures including the absolute configurations of the new compounds were elucidated by spectroscopic methods. All the compounds, except for 2, were evaluated for their in vitro cytotoxic activity against cultured SMMC‐7721 (human hepatoma), HL‐60 (human promyelocytic leukemia), and L02 (human hepatocyte) cells.
doi_str_mv 10.1002/hlca.200890206
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source Wiley Online Library Journals Frontfile Complete
subjects Carpesium triste
Cytotoxic activity
Diterpenoids
title New Acyclic 12-Hydroxygeranylgeraniol-Derived Diterpenoids from the Seeds of Carpesium triste
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