Efficient Synthesis of Functionalized Thiazoles from Acid Chlorides, Tetramethylthiourea, Ethyl Bromopyruvate, and Ammonium Thiocyanate

An efficient synthesis of ethyl 2‐(dimethylamino)‐1,3‐thiazole‐4‐carboxylates is described via a four‐component reaction between acid chlorides, tetramethylthiourea, ethyl bromopyruvate, and ammonium thiocyanate.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Helvetica chimica acta 2008-06, Vol.91 (6), p.1177-1180
Hauptverfasser:	Yavari, Issa, Hossaini, Zinatossadat, Seyfi, Samereh, Shirgahi-Talari, Faezeh
Format:	Artikel
Sprache:	eng
Schlagworte:	1,3‐Thiazole‐4‐carboxylates 3-Thiazole-4-carboxylates Multicomponent synthesis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	An efficient synthesis of ethyl 2‐(dimethylamino)‐1,3‐thiazole‐4‐carboxylates is described via a four‐component reaction between acid chlorides, tetramethylthiourea, ethyl bromopyruvate, and ammonium thiocyanate.
ISSN:	0018-019X 1522-2675
DOI:	10.1002/hlca.200890127