A Triterpenoid and Sesquiterpenoids from the Resinous Exudates of Commiphora myrrha

A Triterpenoid and Sesquiterpenoids from the Resinous Exudates of Commiphora myrrha

A new 30(14→13)abeo‐dammarane triterpenoid, myrrhasin (1), a new 14(10→1)abeo‐eudesmane sesquiterpenoid, myrrhanolide A (2), and two new cadinane sesquiterpenoids, myrrhanolides B and C (3 and 4, resp.), as well as nine known sesquiterpenoids, 5–13, were isolated from the resinous exudates of Commip...

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Veröffentlicht in:Helvetica chimica acta 2009-04, Vol.92 (4), p.645-652
Hauptverfasser: Shen, Tao, Wan, Wen-Zhu, Wang, Xiao-Ning, Yuan, Hui-Qing, Ji, Mei, Lou, Hong-Xiang
Format: Artikel
Sprache:eng
Schlagworte:
Commiphora myrrha
Cytotoxic activity
Myrrhanolides A - C
Myrrhasin
Sesquiterpenoids
Triterpenoids
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Zusammenfassung:A new 30(14→13)abeo‐dammarane triterpenoid, myrrhasin (1), a new 14(10→1)abeo‐eudesmane sesquiterpenoid, myrrhanolide A (2), and two new cadinane sesquiterpenoids, myrrhanolides B and C (3 and 4, resp.), as well as nine known sesquiterpenoids, 5–13, were isolated from the resinous exudates of Commiphora myrrha. Their structures were determined on the basis of extensive MS and NMR spectroscopic analyses. The isolated compounds 1–6 were evaluated for their cytotoxicity against the PC3 and DU145 human prostate tumor cell lines.
ISSN:0018-019X
1522-2675
DOI:10.1002/hlca.200800347