One-Pot Three-Component Synthesis of α-Amino Nitriles Catalyzed by 2,4,6-Trichloro-1,3,5-triazine (Cyanuric Acid)
A simple and efficient method has been developed for the synthesis of α‐amino nitriles from aldehydes, amines and trimethylsilyl cyanide (Me3SiCN) in the presence of a catalytic amount of cyanuric acid at room temperature.
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| Veröffentlicht in: | Helvetica chimica acta 2007-06, Vol.90 (6), p.1206-1210 |
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| container_title | Helvetica chimica acta |
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| creator | Das, Biswanath Kumar, Rathod Aravind Thirupathi, Ponnaboina |
| description | A simple and efficient method has been developed for the synthesis of α‐amino nitriles from aldehydes, amines and trimethylsilyl cyanide (Me3SiCN) in the presence of a catalytic amount of cyanuric acid at room temperature. |
| doi_str_mv | 10.1002/hlca.200790119 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0018-019X |
| ispartof | Helvetica chimica acta, 2007-06, Vol.90 (6), p.1206-1210 |
| issn | 0018-019X 1522-2675 |
| language | eng |
| recordid | cdi_crossref_primary_10_1002_hlca_200790119 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | 1,3,5‐Triazine, 2,4,6‐trichloro 5-Triazine 6-trichloro Cyanuric acid Nitriles Nitriles, α‐amino One-pot three-component synthesis Strecker-type reaction Trimethylsilyl cyanide α-amino |
| title | One-Pot Three-Component Synthesis of α-Amino Nitriles Catalyzed by 2,4,6-Trichloro-1,3,5-triazine (Cyanuric Acid) |
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