Facile One-Pot Three-Component Synthesis of Functionalized Pyridylfuran-2-amines

Facile One-Pot Three-Component Synthesis of Functionalized Pyridylfuran-2-amines

The reactive 1 : 1 zwitterionic intermediates generated in situ from the reaction between a series of isocyanides and diaroylacetylenes were trapped by pyridine carbaldehydes to yield highly functionalized 5‐pyridylfuran‐2‐amines in good yields (82–93%).

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Bibliographische Detailangaben
Veröffentlicht in:Helvetica chimica acta 2006-02, Vol.89 (2), p.299-303
Hauptverfasser: Adib, Mehdi, Sayahi, Mohammad Hosein, Koloogani, Somayeh Aali, Mirzaei, Peiman
Format: Artikel
Sprache:eng
Schlagworte:
Acetylenes
Acetylenes, diaroyl
diaroyl
Isocyanides
Pyridylfuran-2-amines
Three-component synthesis
Zwitterionic intermediates
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Beschreibung
Zusammenfassung:The reactive 1 : 1 zwitterionic intermediates generated in situ from the reaction between a series of isocyanides and diaroylacetylenes were trapped by pyridine carbaldehydes to yield highly functionalized 5‐pyridylfuran‐2‐amines in good yields (82–93%).
ISSN:0018-019X
1522-2675
DOI:10.1002/hlca.200690034