Synthesis and Properties of O-β-D-ribofuranosyl-(1″→2′)-guanosine-5″- O-phosphate and Its Derivatives

The efficient synthesis of O‐β‐D‐ribofuranosyl‐(1″→2′)‐guanosine‐5″‐O‐phosphate and O‐β‐D‐ribofuranosyl‐(1″→2′)‐adenosine‐5″‐O‐phosphate, minor tRNA components, have been developed, and their conformational properties were examined by NMR spectroscopy....

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Veröffentlicht in:Helvetica chimica acta 2003-02, Vol.86 (2), p.504-514
Hauptverfasser: Efimtseva, Ekaterina V., Shelkunova, Alexandra A., Mikhailov, Sergey N., Nauwelaerts, Koen, Rozenski, Jef, Lescrinier, Eveline, Herdewijn, Piet
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Sprache:eng
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Zusammenfassung:The efficient synthesis of O‐β‐D‐ribofuranosyl‐(1″→2′)‐guanosine‐5″‐O‐phosphate and O‐β‐D‐ribofuranosyl‐(1″→2′)‐adenosine‐5″‐O‐phosphate, minor tRNA components, have been developed, and their conformational properties were examined by NMR spectroscopy.
ISSN:0018-019X
1522-2675
DOI:10.1002/hlca.200390050