Synthèse et configuration absolue des énantiomères du Vér apamil
Synthesis and Absolute Confifguration of the Enantiomers of Verapamil. Starting from the acids IV‐(+) and IV‐(−), a synthesis of the enantiomers I‐(+) and I‐(−) of the coronary vasodilator Verapamil is described and their absolute configuration determined through a chemical filiation with the acid X...
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| Veröffentlicht in: | Helvetica chimica acta 1975-11, Vol.58 (7), p.2050-2060 |
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| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Synthesis and Absolute Confifguration of the Enantiomers of Verapamil.
Starting from the acids IV‐(+) and IV‐(−), a synthesis of the enantiomers I‐(+) and I‐(−) of the coronary vasodilator Verapamil is described and their absolute configuration determined through a chemical filiation with the acid XII‐(S)‐(+). |
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| ISSN: | 0018-019X 1522-2675 |
| DOI: | 10.1002/hlca.19750580720 |