Five new alleles of plasma Zn-alpha 2-glycoprotein variants phenotyped by isoelectric focusing and immunoblotting in twelve populations

Five new alleles of plasma Zn-alpha 2-glycoprotein variants phenotyped by isoelectric focusing and immunoblotting in twelve populations

Human Zn‐alpha 2‐glycoprotein (ZAG) in plasma samples from twelve populations was tested by immunoblotting after polyacrylamide gel isoelectric focusing. Eleven ZAG phenotypes produced by one common and nine rare alleles, including five new ones (ZAG*6–ZAG*10), were detected. Additionally, an applic...

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Veröffentlicht in:Electrophoresis 1992, Vol.13 (1), p.154-157
Hauptverfasser: Nakayashiki, Nori, Umetsu, Kazuo, Yuasa, Isao, Suenaga, Kazuyuki, Omoto, Keiichi, Ishida, Takafumi, Misawa, Shogo, Katsura, Syusaku
Format: Artikel
Sprache:eng
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Zusammenfassung:Human Zn‐alpha 2‐glycoprotein (ZAG) in plasma samples from twelve populations was tested by immunoblotting after polyacrylamide gel isoelectric focusing. Eleven ZAG phenotypes produced by one common and nine rare alleles, including five new ones (ZAG*6–ZAG*10), were detected. Additionally, an application of separator IEF with N′‐2‐hydroxyethylpiperazine‐N′‐2‐ethanesulfonic acid (HEPES) was found to be useful for discriminating the rare ZAG 7 band.
ISSN:0173-0835
1522-2683
DOI:10.1002/elps.1150130131