Simultaneous Molecular Recognition of Interleukins 2 and 4, and of Tumour Necrosis Factor‐α in Biological Samples

Two 3D stochastic sensors based on single‐walled carbon nanotubes and multi‐walled carbon nanotubes decorated with gold nanoparticles and modified with 5,10,15,20‐tetrakis (pentafluorophenyl)‐21H,23H‐porphyrin iron (III) chloride were constructed and utilized for the simultaneous molecular recogniti...

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Veröffentlicht in:Electroanalysis (New York, N.Y.) N.Y.), 2023-03, Vol.35 (3), p.n/a
Hauptverfasser: Cioates Negut, Catalina, Stefan‐van Staden, Raluca‐Ioana, Sfirloaga, Paula
Format: Artikel
Sprache:eng
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Zusammenfassung:Two 3D stochastic sensors based on single‐walled carbon nanotubes and multi‐walled carbon nanotubes decorated with gold nanoparticles and modified with 5,10,15,20‐tetrakis (pentafluorophenyl)‐21H,23H‐porphyrin iron (III) chloride were constructed and utilized for the simultaneous molecular recognition of IL‐2, IL‐4, and TNF‐α in biological samples. The proposed sensors present low limits of quantification, high sensitivity, and wide concentration ranges. Recoveries values higher than 98.2 % of analytes from whole blood and brain tumour tissue samples were obtained.
ISSN:1040-0397
1521-4109
DOI:10.1002/elan.202200305