Graphene Oxide Modified Carbon Paste Electrode for Handy and Ultra‐sensitive Determination of Epinephrine in the Presence of Uric and Ascorbic Acids

A precise and sensitive electrochemical sensor based on a simple graphene oxide modified carbon paste electrode (GO/CPE) was successfully fabricated for simultaneous detection of epinephrine (EPN), uric acid (UA), and ascorbic acid (AA). The GO/CPE displays better electrochemical activity towards EPN by largely improving the current sensitivity and selectivity. Large peak separation allowed this sensor to analyze EPN individually and simultaneously in the mixture of AA and UA. The developed sensor showed good reproducibility, and stability. The sensor exhibited acceptable performance in wide concentration range (0.1–2000 μM) with a limit of detection down to 50 nM.