Front Cover: Late‐Stage Functionalisation of Pyridine‐Containing Bioactive Molecules: Recent Strategies and Perspectives (Eur. J. Org. Chem. 16/2023)

The Front Cover Cover illustrates how the pyridine ring of the antihistamine loratadine can be selectively functionalised at the ortho‐, meta‐, or para‐position (each of them activated by a thunder). Indeed, the selective functionalisation of this N‐heterocycle is often problematic, thus a lighthous...

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Veröffentlicht in:European journal of organic chemistry 2023-04, Vol.26 (16), p.n/a
Hauptverfasser: Failla, Mattia, Lombardo, Giacomo W., Orlando, Paolo, Fiorito, Daniele, Bombonato, Elena, Ronchi, Paolo, Passarella, Daniele, Fasano, Valerio
Format: Artikel
Sprache:eng
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Zusammenfassung:The Front Cover Cover illustrates how the pyridine ring of the antihistamine loratadine can be selectively functionalised at the ortho‐, meta‐, or para‐position (each of them activated by a thunder). Indeed, the selective functionalisation of this N‐heterocycle is often problematic, thus a lighthouse guides the chemists through the late‐stage functionalisations of pyridine‐containing biomolecules. More information can be found in the Review by V. Fasano et al.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.202300272