Cover Feature: An Improved Protocol for the Morita‐Baylis‐Hillman Reaction Allows Unprecedented Broad Synthetic Scope (Eur. J. Org. Chem. 9/2022)

The Cover Feature illustrates the effect of acetic acid on the rate of the Morita–Baylis–Hillman reaction. The use of acetic acid as a fuel (additive) increases the reaction rate in all tested cases, with special emphasis on electron‐rich electrophilic partners. We believe that a general acid cataly...

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Veröffentlicht in:European journal of organic chemistry 2022-03, Vol.2022 (9), p.n/a
Hauptverfasser: Camilo, Nilton S., Santos, Hugo, Zeoly, Lucas A., Fernandes, Fábio S., Rodrigues, Manoel T., Silva, Thiago S., Lima, Samia R., Serafim, José Cláudio, Oliveira, Aline S. B., Carpanez, Arthur G., Amarante, Giovanni W., Coelho, Fernando
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Sprache:eng
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Zusammenfassung:The Cover Feature illustrates the effect of acetic acid on the rate of the Morita–Baylis–Hillman reaction. The use of acetic acid as a fuel (additive) increases the reaction rate in all tested cases, with special emphasis on electron‐rich electrophilic partners. We believe that a general acid catalysis mechanism is responsible for this increase in reaction rate. More information can be found in the Research Article by G. W. Amarante, F. Coelho et al.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.202200183