KI‐Mediated One‐Pot Transition‐Metal‐Rree Synthesis of 4‐Phenylpyrrolo[1,2‐a]quinoxalines

KI‐Mediated One‐Pot Transition‐Metal‐Rree Synthesis of 4‐Phenylpyrrolo[1,2‐a]quinoxalines

An efficient and eco‐friendly method for the synthesis of pyrrolo[1,2‐a]quinoxalines is presented. Compared to previous methods, this protocol is transition‐metal‐free and only potassium iodide is required. A series of substituted 4‐phenylpyrrolo[1,2‐a]quinoxalines are obtained in moderate to good y...

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Veröffentlicht in:European journal of organic chemistry 2020-08, Vol.2020 (31), p.4950-4956
Hauptverfasser: Li, Shichen, Xie, Caixia, Chu, Xianglong, Dai, Zhen, Feng, Lei, Ma, Chen
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One‐pot
Pyrrolo[1,2‐a]quinoxalines
Transition‐metal‐free
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container_issue 31
container_start_page 4950
container_title European journal of organic chemistry
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creator Li, Shichen
Xie, Caixia
Chu, Xianglong
Dai, Zhen
Feng, Lei
Ma, Chen
description An efficient and eco‐friendly method for the synthesis of pyrrolo[1,2‐a]quinoxalines is presented. Compared to previous methods, this protocol is transition‐metal‐free and only potassium iodide is required. A series of substituted 4‐phenylpyrrolo[1,2‐a]quinoxalines are obtained in moderate to good yields. This protocol offered an eco‐friendly and convenient method for the synthesis of pyrrolo[1,2‐a]quinoxalines. In this process, new C=N and C–C bond were formed in mild conditions. A series of pyrrolo[1,2‐a]quinoxaline derivatives were obtained in moderate to good yields.
doi_str_mv 10.1002/ejoc.202000791
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subjects One‐pot
Pyrrolo[1,2‐a]quinoxalines
Transition‐metal‐free
title KI‐Mediated One‐Pot Transition‐Metal‐Rree Synthesis of 4‐Phenylpyrrolo[1,2‐a]quinoxalines
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