Hydroxamic Acids − An Intriguing Family of Enzyme Inhibitors and Biomedical Ligands

Hydroxamic Acids − An Intriguing Family of Enzyme Inhibitors and Biomedical Ligands

This review on hydroxamic acids deals with their efficacy as inhibitors of enzymes including cyclooxygenases, their synthesis, the complexity and structural diversity of their metal complexes, and their ability to act as effective nitric oxide donors. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 W...

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Veröffentlicht in:European journal of inorganic chemistry 2004-08, Vol.2004 (15), p.3003-3016
Hauptverfasser: Marmion, Celine J., Griffith, Darren, Nolan, Kevin B.
Format: Artikel
Sprache:eng
Schlagworte:
Chelates
Cyclooxygenase
Enzyme inhibitors
Hydroxamic acids
Nitric oxide donors
Siderophores
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Zusammenfassung:This review on hydroxamic acids deals with their efficacy as inhibitors of enzymes including cyclooxygenases, their synthesis, the complexity and structural diversity of their metal complexes, and their ability to act as effective nitric oxide donors. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
ISSN:1434-1948
1099-0682
DOI:10.1002/ejic.200400221