Nurr1 blocks the mitogenic effect of FGF ‐2 and EGF , inducing olfactory bulb neural stem cells to adopt dopaminergic and dopaminergic‐ GABA ergic neuronal phenotypes

The transcription factor Nurr1 is expressed in the mouse olfactory bulb (OB), although it remains unknown whether it influences the generation of dopaminergic neurons (DA) (DA neurons) in cells isolated from this brain region. We found that expressing Nurr1 in proliferating olfactory bulb stem cells...

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Veröffentlicht in:Developmental neurobiology (Hoboken, N.J.) N.J.), 2015-08, Vol.75 (8), p.823-841
Hauptverfasser: Vergaño‐Vera, Eva, Díaz‐Guerra, Eva, Rodríguez‐Traver, Eva, Méndez‐Gómez, Héctor R., Solís, Óscar, Pignatelli, Jaime, Pickel, James, Lee, Sang‐Hun, Moratalla, Rosario, Vicario‐Abejón, Carlos
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Sprache:eng
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