A Novel Stereoselective Synthesis of (1Z,3E)-2-Phenyl(or p-Tolyl)sulfonyl-substituted 1,3-Dienes via Palladium Catalyzed Cross-coupling Reactions of (E)-α-Iodovinyl Sulfones

A Novel Stereoselective Synthesis of (1Z,3E)-2-Phenyl(or p-Tolyl)sulfonyl-substituted 1,3-Dienes via Palladium Catalyzed Cross-coupling Reactions of (E)-α-Iodovinyl Sulfones

(E)‐α‐Stannylvinyl phenyl(or p‐tolyl)sulfones underwent an iododestannylation reaction to afford (E)‐α‐iodovinyl phenyl(or p‐tolyl)sulfones 1, which reacted with (E)‐alkenylzirconium(IV) complexes 2 produced in situ by hydrozirconation of terminal alkynes in the presence of a Pd(PPh3)4 catalyst to a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chinese journal of chemistry 2007-12, Vol.25 (12), p.1927-1931
Hauptverfasser: HU, Rong-Hua, CHEN, Gui-Qin, CAI, Ming-Zhong
Format: Artikel
Sprache:eng
Schlagworte:
(E)-α-iodovinyl sulfone
1,3‐dien‐2‐yl sulfone
3-dien-2-yl sulfone
cross-coupling
hydrozirconation
palladium
palladium, cross‐coupling
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:(E)‐α‐Stannylvinyl phenyl(or p‐tolyl)sulfones underwent an iododestannylation reaction to afford (E)‐α‐iodovinyl phenyl(or p‐tolyl)sulfones 1, which reacted with (E)‐alkenylzirconium(IV) complexes 2 produced in situ by hydrozirconation of terminal alkynes in the presence of a Pd(PPh3)4 catalyst to afford stereoselectively (1Z,3E)‐2‐ phenyl(or p‐tolyl)sulfonyl‐substituted 1,3‐dienes 3 in good yields.
ISSN:1001-604X
1614-7065
DOI:10.1002/cjoc.200790355