5-Fluorouracil derivatives XXIII. Synthesis and antitumor activities of 1-carbamoyl-5-fluorouracils having aromatic ring

In order to get good antitumor agents especially better than 5‐fluorouracil, tegafur and l‐hexylcarbamoyl‐5‐fluorouracil (HCFU), fourty nine 1‐carbamoyl‐5‐fluorouracil having aromatic ring were synthesized from 5‐fluorouracil and isocyanates or mines. Antitumor activity was tested in the L1210 tumor...

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Veröffentlicht in:	Chinese journal of chemistry 1998-03, Vol.16 (2), p.171-177
Hauptverfasser:	Shoichiro, Ozaki, Xiang-Zheng, Kong, Yutaka, Watanabe, Tomonori, Hoshiko, Tomio, Ogasawara, Takao, Ueno, Uiroyuki, Furukawa, Masaaki, Iigo, Akio, Hoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	1-(p-iso-propylbenzyl)-5-fluorouracil Antitumor agent aromatic carbamoyl-5-fluorouracil l-(p-methoxybenzyl)-5-fluorouracil
Online-Zugang:	Volltext
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