ChemInform Abstract: Stereochemical Determination of the Leupyrrins and Total Synthesis of Leupyrrin A 1

ChemInform Abstract: Stereochemical Determination of the Leupyrrins and Total Synthesis of Leupyrrin A 1

The relative and absolute configurations of potent antifungal agents leupyrrin A 1 (I) and B 1 (II) are determined by a combination of high field NMR studies, molecular modeling, and chemical derivatization.

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Veröffentlicht in:ChemInform 2015-09, Vol.46 (35)
Hauptverfasser: Herkommer, Daniel, Thiede, Sebastian, Wosniok, Paul R., Dreisigacker, Sandra, Tian, Maoqun, Debnar, Thomas, Irschik, Herbert, Menche, Dirk
Format: Artikel
Sprache:eng
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Zusammenfassung:The relative and absolute configurations of potent antifungal agents leupyrrin A 1 (I) and B 1 (II) are determined by a combination of high field NMR studies, molecular modeling, and chemical derivatization.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201535239