ChemInform Abstract: Synthesis of 2-Aryl-3-(2-cyanoethyl)aziridines and Their Chemical and Enzymatic Hydrolysis Towards γ-Lactams and γ-Lactones
The title compounds (IV) are transformed into variable mixtures of 4‐[aryl(alkylamino)methyl]butyrolactones and 5‐[aryl(hydroxy)methyl]pyrrolidin‐2‐ones by KOH‐mediated hydrolysis of the cyano group, followed by ring expansion.
Gespeichert in:
| Veröffentlicht in: | ChemInform 2015-07, Vol.46 (27), p.no-no |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | no |
|---|---|
| container_issue | 27 |
| container_start_page | no |
| container_title | ChemInform |
| container_volume | 46 |
| creator | Mollet, Karen Decuyper, Lena Vander Meeren, Saskia Piens, Nicola De Winter, Karel Desmet, Tom D'hooghe, Matthias |
| description | The title compounds (IV) are transformed into variable mixtures of 4‐[aryl(alkylamino)methyl]butyrolactones and 5‐[aryl(hydroxy)methyl]pyrrolidin‐2‐ones by KOH‐mediated hydrolysis of the cyano group, followed by ring expansion. |
| doi_str_mv | 10.1002/chin.201527134 |
| format | Article |
| fullrecord | <record><control><sourceid>wiley_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1002_chin_201527134</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CHIN201527134</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1274-1b06cdb5444d7e5de37e5954636f3aad4f445d47645db1a813d07b759527d5c83</originalsourceid><addsrcrecordid>eNqFkDtOAzEQhi0EEuHRUruEwmH92HVCF4XARgqhSBB0ltf2ag37QPZKYI7BVbgHZ8IhCNHRzIyt-f6RPgBOcDLESULOVWXbIUlwSjimbAcM4kQQyTK-CwbJmGLE0zHfBwfeP8Z9ykdkAN6nlWnmbdm5Bk4K3zup-gu4Cm1fGW897EpI0MSFGlF0SpAKsu1MX4X6TL5ZZ7VtjYey1XBdGevgJs0qWX9_zdq30MjeKpgH7bo6bALX3Yt02sPPD7SIt2SzxX-eXYw7AnulrL05_umH4O5qtp7maHF7PZ9OFkhhwhnCRZIpXaSMMc1Nqg2NdZyyjGYllVKzkrFUM57FWmA5wlQnvIgKoh-dqhE9BMNtrnKd986U4tnZRrogcCI2RsXGqPg1GoHxFnixtQn_bItpPl_-ZdGWtb43r7-sdE8i45Sn4n55LfKrfHVz-UDFPf0CLOaMog</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>ChemInform Abstract: Synthesis of 2-Aryl-3-(2-cyanoethyl)aziridines and Their Chemical and Enzymatic Hydrolysis Towards γ-Lactams and γ-Lactones</title><source>Wiley Online Library - AutoHoldings Journals</source><creator>Mollet, Karen ; Decuyper, Lena ; Vander Meeren, Saskia ; Piens, Nicola ; De Winter, Karel ; Desmet, Tom ; D'hooghe, Matthias</creator><creatorcontrib>Mollet, Karen ; Decuyper, Lena ; Vander Meeren, Saskia ; Piens, Nicola ; De Winter, Karel ; Desmet, Tom ; D'hooghe, Matthias</creatorcontrib><description>The title compounds (IV) are transformed into variable mixtures of 4‐[aryl(alkylamino)methyl]butyrolactones and 5‐[aryl(hydroxy)methyl]pyrrolidin‐2‐ones by KOH‐mediated hydrolysis of the cyano group, followed by ring expansion.</description><identifier>ISSN: 0931-7597</identifier><identifier>EISSN: 1522-2667</identifier><identifier>DOI: 10.1002/chin.201527134</identifier><language>eng</language><publisher>Weinheim: WILEY-VCH Verlag</publisher><subject>aziridine derivatives ; biochemical syntheses ; biochemical syntheses, microbiological syntheses ; furan derivatives ; mechanochemistry ; microbiological syntheses ; microwave chemistry ; microwave chemistry, sonochemistry, mechanochemistry ; pyrrole derivatives ; ring contraction ; ring expansion ; sonochemistry</subject><ispartof>ChemInform, 2015-07, Vol.46 (27), p.no-no</ispartof><rights>2015 WILEY‐VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1274-1b06cdb5444d7e5de37e5954636f3aad4f445d47645db1a813d07b759527d5c83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fchin.201527134$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fchin.201527134$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids></links><search><creatorcontrib>Mollet, Karen</creatorcontrib><creatorcontrib>Decuyper, Lena</creatorcontrib><creatorcontrib>Vander Meeren, Saskia</creatorcontrib><creatorcontrib>Piens, Nicola</creatorcontrib><creatorcontrib>De Winter, Karel</creatorcontrib><creatorcontrib>Desmet, Tom</creatorcontrib><creatorcontrib>D'hooghe, Matthias</creatorcontrib><title>ChemInform Abstract: Synthesis of 2-Aryl-3-(2-cyanoethyl)aziridines and Their Chemical and Enzymatic Hydrolysis Towards γ-Lactams and γ-Lactones</title><title>ChemInform</title><addtitle>ChemInform</addtitle><description>The title compounds (IV) are transformed into variable mixtures of 4‐[aryl(alkylamino)methyl]butyrolactones and 5‐[aryl(hydroxy)methyl]pyrrolidin‐2‐ones by KOH‐mediated hydrolysis of the cyano group, followed by ring expansion.</description><subject>aziridine derivatives</subject><subject>biochemical syntheses</subject><subject>biochemical syntheses, microbiological syntheses</subject><subject>furan derivatives</subject><subject>mechanochemistry</subject><subject>microbiological syntheses</subject><subject>microwave chemistry</subject><subject>microwave chemistry, sonochemistry, mechanochemistry</subject><subject>pyrrole derivatives</subject><subject>ring contraction</subject><subject>ring expansion</subject><subject>sonochemistry</subject><issn>0931-7597</issn><issn>1522-2667</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNqFkDtOAzEQhi0EEuHRUruEwmH92HVCF4XARgqhSBB0ltf2ag37QPZKYI7BVbgHZ8IhCNHRzIyt-f6RPgBOcDLESULOVWXbIUlwSjimbAcM4kQQyTK-CwbJmGLE0zHfBwfeP8Z9ykdkAN6nlWnmbdm5Bk4K3zup-gu4Cm1fGW897EpI0MSFGlF0SpAKsu1MX4X6TL5ZZ7VtjYey1XBdGevgJs0qWX9_zdq30MjeKpgH7bo6bALX3Yt02sPPD7SIt2SzxX-eXYw7AnulrL05_umH4O5qtp7maHF7PZ9OFkhhwhnCRZIpXaSMMc1Nqg2NdZyyjGYllVKzkrFUM57FWmA5wlQnvIgKoh-dqhE9BMNtrnKd986U4tnZRrogcCI2RsXGqPg1GoHxFnixtQn_bItpPl_-ZdGWtb43r7-sdE8i45Sn4n55LfKrfHVz-UDFPf0CLOaMog</recordid><startdate>201507</startdate><enddate>201507</enddate><creator>Mollet, Karen</creator><creator>Decuyper, Lena</creator><creator>Vander Meeren, Saskia</creator><creator>Piens, Nicola</creator><creator>De Winter, Karel</creator><creator>Desmet, Tom</creator><creator>D'hooghe, Matthias</creator><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><scope>BSCLL</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>201507</creationdate><title>ChemInform Abstract: Synthesis of 2-Aryl-3-(2-cyanoethyl)aziridines and Their Chemical and Enzymatic Hydrolysis Towards γ-Lactams and γ-Lactones</title><author>Mollet, Karen ; Decuyper, Lena ; Vander Meeren, Saskia ; Piens, Nicola ; De Winter, Karel ; Desmet, Tom ; D'hooghe, Matthias</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1274-1b06cdb5444d7e5de37e5954636f3aad4f445d47645db1a813d07b759527d5c83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>aziridine derivatives</topic><topic>biochemical syntheses</topic><topic>biochemical syntheses, microbiological syntheses</topic><topic>furan derivatives</topic><topic>mechanochemistry</topic><topic>microbiological syntheses</topic><topic>microwave chemistry</topic><topic>microwave chemistry, sonochemistry, mechanochemistry</topic><topic>pyrrole derivatives</topic><topic>ring contraction</topic><topic>ring expansion</topic><topic>sonochemistry</topic><toplevel>online_resources</toplevel><creatorcontrib>Mollet, Karen</creatorcontrib><creatorcontrib>Decuyper, Lena</creatorcontrib><creatorcontrib>Vander Meeren, Saskia</creatorcontrib><creatorcontrib>Piens, Nicola</creatorcontrib><creatorcontrib>De Winter, Karel</creatorcontrib><creatorcontrib>Desmet, Tom</creatorcontrib><creatorcontrib>D'hooghe, Matthias</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><jtitle>ChemInform</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mollet, Karen</au><au>Decuyper, Lena</au><au>Vander Meeren, Saskia</au><au>Piens, Nicola</au><au>De Winter, Karel</au><au>Desmet, Tom</au><au>D'hooghe, Matthias</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>ChemInform Abstract: Synthesis of 2-Aryl-3-(2-cyanoethyl)aziridines and Their Chemical and Enzymatic Hydrolysis Towards γ-Lactams and γ-Lactones</atitle><jtitle>ChemInform</jtitle><addtitle>ChemInform</addtitle><date>2015-07</date><risdate>2015</risdate><volume>46</volume><issue>27</issue><spage>no</spage><epage>no</epage><pages>no-no</pages><issn>0931-7597</issn><eissn>1522-2667</eissn><abstract>The title compounds (IV) are transformed into variable mixtures of 4‐[aryl(alkylamino)methyl]butyrolactones and 5‐[aryl(hydroxy)methyl]pyrrolidin‐2‐ones by KOH‐mediated hydrolysis of the cyano group, followed by ring expansion.</abstract><cop>Weinheim</cop><pub>WILEY-VCH Verlag</pub><doi>10.1002/chin.201527134</doi><tpages>1</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0931-7597 |
| ispartof | ChemInform, 2015-07, Vol.46 (27), p.no-no |
| issn | 0931-7597 1522-2667 |
| language | eng |
| recordid | cdi_crossref_primary_10_1002_chin_201527134 |
| source | Wiley Online Library - AutoHoldings Journals |
| subjects | aziridine derivatives biochemical syntheses biochemical syntheses, microbiological syntheses furan derivatives mechanochemistry microbiological syntheses microwave chemistry microwave chemistry, sonochemistry, mechanochemistry pyrrole derivatives ring contraction ring expansion sonochemistry |
| title | ChemInform Abstract: Synthesis of 2-Aryl-3-(2-cyanoethyl)aziridines and Their Chemical and Enzymatic Hydrolysis Towards γ-Lactams and γ-Lactones |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T18%3A05%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-wiley_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=ChemInform%20Abstract:%20Synthesis%20of%202-Aryl-3-(2-cyanoethyl)aziridines%20and%20Their%20Chemical%20and%20Enzymatic%20Hydrolysis%20Towards%20%CE%B3-Lactams%20and%20%CE%B3-Lactones&rft.jtitle=ChemInform&rft.au=Mollet,%20Karen&rft.date=2015-07&rft.volume=46&rft.issue=27&rft.spage=no&rft.epage=no&rft.pages=no-no&rft.issn=0931-7597&rft.eissn=1522-2667&rft_id=info:doi/10.1002/chin.201527134&rft_dat=%3Cwiley_cross%3ECHIN201527134%3C/wiley_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |