ChemInform Abstract: Synthesis of 12,12a-Dihydro-7,12a-diazacyclohepta[cd]benz[g]azulen-12-one (Cyclohepta[mn]pyrrolo[2,1-c][1,4]benzodiazepin-12-one) and Evaluation of Cytotoxic Activity Against HeLa S3 Cells
The synthesis of the new title pyrrolobenzodiazepine (IV) is described, which exhibits strong cytotoxic activity against HeLa S3 cells.
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| Veröffentlicht in: | ChemInform 2011-10, Vol.42 (43), p.no-no |
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| container_title | ChemInform |
| container_volume | 42 |
| creator | Yoshioka, Eiko Fujii, Hiroyuki Murafuji, Toshihiro Ikeda, Reiko Konakahara, Takeo Gunji, Takahiro Abe, Noritaka |
| description | The synthesis of the new title pyrrolobenzodiazepine (IV) is described, which exhibits strong cytotoxic activity against HeLa S3 cells. |
| doi_str_mv | 10.1002/chin.201143163 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0931-7597 |
| ispartof | ChemInform, 2011-10, Vol.42 (43), p.no-no |
| issn | 0931-7597 1522-2667 |
| language | eng |
| recordid | cdi_crossref_primary_10_1002_chin_201143163 |
| source | Wiley Online Library All Journals |
| subjects | anticancer activity anticarcinogenic activity anticarcinogenic activity, anticancer activity multi-membered N-heterocycles ring closure reactions |
| title | ChemInform Abstract: Synthesis of 12,12a-Dihydro-7,12a-diazacyclohepta[cd]benz[g]azulen-12-one (Cyclohepta[mn]pyrrolo[2,1-c][1,4]benzodiazepin-12-one) and Evaluation of Cytotoxic Activity Against HeLa S3 Cells |
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