ChemInform Abstract: An Efficient One-Pot Synthesis of Benzothiazolo-4β-anilino-podophyllotoxin Congeners: DNA Topoisomerase-II Inhibition and Anticancer Activity

Title compounds (III) and (IV), respectively are prepared by employing ZrCl4/NaI reagent system to form highly reactive 4β‐iodo intermediates in the initiatory step.

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Veröffentlicht in:ChemInform 2011-05, Vol.42 (20), p.no-no
Hauptverfasser: Kamal, Ahmed, Kumar, B. Ashwini, Suresh, Paidakula, Shankaraiah, Nagula, Kumar, M. Shiva
Format: Artikel
Sprache:eng
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Zusammenfassung:Title compounds (III) and (IV), respectively are prepared by employing ZrCl4/NaI reagent system to form highly reactive 4β‐iodo intermediates in the initiatory step.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201120194