ChemInform Abstract: 1,3-Dipolar Cycloaddition of Azomethine Ylides to Aldehydes: Synthesis of anti α-Amino-β-hydroxy Esters

Azomethine ylides are generated by thermolysis of aziridines and adds to aldehydes.The obtained oxazolines are readily hydrolyzed to the corresponding anti‐α‐amino‐β‐alcohols.

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Bibliographische Detailangaben
Veröffentlicht in:	ChemInform 2011-04, Vol.42 (17), p.no-no
Hauptverfasser:	Danielsson, Jakob, Toom, Lauri, Somfai, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	aminocarboxylic acids (hydrazinocarboxylic acids) and esters (benzene compounds) cycloaddition reactions diastereoselective syntheses diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism) enantioselective syntheses (incl. cis/trans-isomerism) ring opening reactions
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Beschreibung
Zusammenfassung:	Azomethine ylides are generated by thermolysis of aziridines and adds to aldehydes.The obtained oxazolines are readily hydrolyzed to the corresponding anti‐α‐amino‐β‐alcohols.
ISSN:	0931-7597 1522-2667
DOI:	10.1002/chin.201117080