ChemInform Abstract: Ternary Condensation of Biginelli Thiones, Chloroacetic Acid, and Aldehydes as an Effective Approach Towards Thiazolo[3,2-a]pyrimidines and 5-Arylidenethiazolidine-2,4-diones
The three‐component reaction of thiones (I) with aldehydes (II) and chloroacetic acid readily affords thiazolo[3,2‐a]pyrimidines (IV), whilst prolonged reaction times leads to the formation of hydrolysis products (V).
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| Veröffentlicht in: | ChemInform 2010-08, Vol.41 (34), p.no-no |
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| creator | Lebedyeva, Iryna O. Povstyanoy, Mykhaylo V. Ryabitskii, Aleksey B. Povstyanoy, Vyacheslav M. |
| description | The three‐component reaction of thiones (I) with aldehydes (II) and chloroacetic acid readily affords thiazolo[3,2‐a]pyrimidines (IV), whilst prolonged reaction times leads to the formation of hydrolysis products (V). |
| doi_str_mv | 10.1002/chin.201034177 |
| format | Article |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | fused pyrimidine derivatives multicomponent reactions ring closure reactions thiazole derivatives |
| title | ChemInform Abstract: Ternary Condensation of Biginelli Thiones, Chloroacetic Acid, and Aldehydes as an Effective Approach Towards Thiazolo[3,2-a]pyrimidines and 5-Arylidenethiazolidine-2,4-diones |
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