Synthesis of Both Enantiomers of a P-Chirogenic 1,2-Bisphospholanoethane Ligand via Convergent Routes and Application to Rhodium-Catalyzed Asymmetric Hydrogenation of CI-1008 (Pregabalin)

Synthesis of Both Enantiomers of a P-Chirogenic 1,2-Bisphospholanoethane Ligand via Convergent Routes and Application to Rhodium-Catalyzed Asymmetric Hydrogenation of CI-1008 (Pregabalin)

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Veröffentlicht in:ChemInform 2003-12, Vol.34 (51), p.no-no
1. Verfasser: Hoge, Garrett
Format: Artikel
Sprache:eng
Schlagworte:
aminocarboxylic acids (hydrazinocarboxylic acids) and esters (acyclic compounds)
aminocarboxylic acids (hydrazinocarboxylic acids) and esters (benzene compounds)
diastereoselective syntheses
diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism)
enantioselective syntheses (incl. cis/trans-isomerism)
nitriles (acyclic compounds)
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Zusammenfassung:For see ChemInform in Full Text.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.200351031